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Interact CardioVasc Thorac Surg 2008;7:463. doi:10.1510/icvts.2007.171447D
© 2008 European Association of Cardio-Thoracic Surgery

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eComment

Avoidance of administration of 1 mg of adrenaline in cardiac arrest after cardiac surgery

Mark K. Reed

Saint Barnabas/Newark Beth-Israel Cardiac Surgical ICU, Newark, New Jersey 07039, USA

Should adrenaline be routinely used by the resuscitation team if a patient suffers a cardiac arrest shortly after cardiac surgery?

Regarding the administration of (intravenous) epinephrine for the early-post-operative cardiac surgical patient after the fact of the occurrence of complete circulatory arrest [1] I am an agnostic.

That said, I have found i.v. bolus epinephrine can occasionally avert the aforementioned scenario for the patient in a rapid downward ‘death spiral’. In my experience this near-arrest physiology results from abrupt vasodilatory decompensation, for example when suddenly coughing (i.e. valsalva condition) as sedation wears off. And here is the point I would like to emphasize. The crucial form of epinephrine here is the 1 mg/10 cc (usually as a ‘Bristoject’ male leur lock adapter). Push and flush 50 to 100 mg (0.5 to 1 cc) and the patient in jeopardy pulls out of the dive just skimming the treetops. Push the ‘arrest dose’ of 1 mg/1 cc and as amply noted by others on this concept, the vasodilatory crisis morphs into a hemorrhagic disaster of busted suture line(s) or cannulation site(s).

In summary: Ban the 1 mg/1 cc epinephrine syringes. Keep the 1 mg/10 cc dosage form handy.


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  1. Tsagkataki M, Levine A, Strang T, Dunning J. Should adrenaline be routinely used by the resuscitation team if a patient suffers a cardiac arrest shortly after cardiac surgery? Interact CardioVasc Thorac Surg 2008;7:457–463.[Abstract/Free Full Text]

Related Article

Should adrenaline be routinely used by the resuscitation team if a patient suffers a cardiac arrest shortly after cardiac surgery?
Myrto Tsagkataki, Adrian Levine, Tim Strang, and Joel Dunning
Interactive CardioVascular and Thoracic Surgery 2008 7: 457-462. [Abstract] [Full Text] [PDF]




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