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Interact CardioVasc Thorac Surg 2007;6:622. doi:10.1510/icvts.2007.155523A
© 2007 European Association of Cardio-Thoracic Surgery

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Institutional report - Cardiopulmonary bypass

ICVTS on-line discussion A Plateletpheresis or aprotinin, which is the key element?

Chung-Dann Kan

National Cheng Kung University Hospital, Tainan 70124, Taiwan

Acute plateletpheresis and aprotinin reduces the need for bloodtransfusion following Ross operation

eComment: From Al-Rashidi's results, one combination of acute preoperative plateletphresis and a low dose of aprotinin usage can reduce the need for blood transfusion following Ross operation [1]. As is well known, the purpose of aprotinin usage in open heart surgery is to minimize the platelets damage and to preserve their function for coagulation. So, it would be interesting to know if it really needs combination therapy or just one strategy is enough? Also, what is the consideration for extremely low dose of aprotinin usage? Can the author give us more information?


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  1. Al-Rashidi F, Bhat M, Pierre L, Koul B. Acute plateletpheresis and aprotinin reduces the need for blood transfusion following Ross operation. Interact CardioVasc Thorac Surg 2007; 6:618–622.[Abstract/Free Full Text]

Related Article

Acute plateletpheresis and aprotinin reduces the need for blood transfusion following Ross operation
Faleh Al-Rashidi, Misha Bhat, Leif Pierre, and Bansi Koul
Interactive CardioVascular and Thoracic Surgery 2007 6: 618-622. [Abstract] [Full Text] [PDF]




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