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Interact CardioVasc Thorac Surg 2006;5:326. doi:10.1510/icvts.2005.122390B
© 2006 European Association of Cardio-Thoracic Surgery
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Institutional report - Cardiac general

ICVTS on-line discussion B

Alexander Wahba

St. Elisabeth Dep. of Heart and Lung Surgery, St. Olavs University Hospital, NTNU Trondheim, Norway

Levosimendan for patients with impaired left ventricular function undergoing cardiac surgery

eComment: We have been using levosimendan in more than 20 patients, where problems with weaning from bypass were expected. This comprised mostly emergency cases and surgery in patients with poor LV function. Ventricular arrhythmias did not appear to be a significant problem. We have the impression that the favourable circulatory effects of levosimendan cannot be explained by vasodilation and an increase in heart rate alone. However, I agree with Ibrahim [1] that the publication by Tokuda et al. [2] does not clarify the role of levosimendan in cardiac surgery.


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  1. Ibrahim MF. ICVTS on-line discussion A. Interact CardioVasc Thorac Surg 2006; 5:326.[Free Full Text]
  2. Tokuda Y, Grant PW, Wolfenden HD, Manganas C, Lyon WJ, Murala JSK. Levosimendan for patients with impaired left ventricular functionundergoing cardiac sugery. Interact CardioVasc Thorac Surg 2006; 5:322–326.[Abstract/Free Full Text]

Related Article

Levosimendan for patients with impaired left ventricular function undergoing cardiac surgery
Yoshiyuki Tokuda, Peter W. Grant, Hugh D. Wolfenden, Con Manganas, William J. Lyon, and John S.K. Murala
Interactive CardioVascular and Thoracic Surgery 2006 5: 322-326. [Abstract] [Full Text] [PDF]




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