Surgery of left ventricular aneurysm: a propensity score-matched study of outcomes following different repair techniques
Zhe Zheng 1,
Hongguang Fan 1,
Wei Feng 1,
Shiju Zhang 1,
Xin Yuan 1,
Liqing Wang 1,
Yunhu Song 1,
Shengshou Hu 1*
1 Peking Union Medical College, Chinese Academy of Medical Science, Beijing, China
* To whom correspondence should be addressed. E-mail: shengshouhu{at}yahoo.com.
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Abstract |
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To evaluate early and late outcomes of modified left ventricular reconstruction (VR) and linear repair (LR) of post-infarct left ventricular aneurysm (LVA). A total of 514 patients were consecutively operated on for LVA with modified VR technique in 145 and LR in 352 patients. Using the propensity score-matching method, we selected 202 patients (101 LRs vs 101 VRs) with similar pre- and intra-operative characteristics and compared their clinical outcomes. After matching, the two groups of patients were similar with regard to baseline data. The increment of left ventricular ejection fraction (LVEF) in VR group was more significant than that in LR group. Operative mortality was 2.0% (2.0% LRs vs 2.0% VRs, p=NS). There was a statistically significant difference between LR and VP patients in MACCEs (29.7% LRs vs 13.9% VRs, p<0.001) and hospital readmissions (51.5% LRs vs 30.7% VRs, p<0.001). Overall long-term mortality and cardiac mortality were the same between the two groups (mortality: 11.9% LRs vs 11.9% VRs, p=NS; cardiac mortality: 9.9% LRs vs 8.9% VRs, p=NS). The technique of repairing LVA did not affect the early and later mortality. Keywords: Left ventricular aneurysm; Linear repair; Left ventricular reconstruction; Propensity score