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Interact CardioVasc Thorac Surg 2009;8:529-533. doi:10.1510/icvts.2008.196303
© 2009 European Association of Cardio-Thoracic Surgery
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Takashi Tojo
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Institutional report - Thoracic non-oncologic

Influence of the site of lobectomy and chronic obstructive pulmonary disease on pulmonary function: a follow-up analysis

Keiji Kushibe*, Takeshi Kawaguchi, Michitaka Kimura, Makoto Takahama, Takashi Tojo and Shigeki Taniguchi

Department of Thoracic and Cardiovascular Surgery, Nara Medical University School of Medicine, Kashihara, Nara, 634-8522, Japan

*Corresponding author. Tel.: +81-744-22-3051; fax: +81-744-24-8040.

E-mail address: mdkeiji{at}m3.kcn.ne.jp (K. Kushibe).

The aim of this retrospective study was to evaluate the influence of the site of lobectomy and the presence of chronic obstructive pulmonary disease (COPD) on pulmonary function at different postoperative periods. The patients were divided into groups of COPD and non-COPD patients, and the differences between observed and predicted postoperative values of pulmonary function at different evaluation times according to the resected lobe were assessed. The observed postoperative percentage change in FEV1 (opo%{Delta}FEV1) – predicted postoperative percentage change in FEV1 (ppo%{Delta}FEV1) one month and six months after right upper lobectomy or left upper lobectomy in COPD patients was of significantly higher positive value than in non-COPD patients. In non-COPD patients, opo%{Delta}FEV1 – ppo%{Delta}FEV1 one month and six months after surgery was of significantly higher negative value in those who had right upper lobectomy than in those who had right lower lobectomy or left lower lobectomy (P<0.05). COPD may strongly influence pulmonary function at early- and late-terms after upper lobectomy. In non-COPD patients, the site of lobectomy may strongly influence pulmonary function at early- and late-terms after surgery.

Key Words: Chronic obstructive pulmonary disease; Lobectomy; Predicted postoperative pulmonary function; Observed postoperative pulmonary function; Postoperative period

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