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Interact CardioVasc Thorac Surg 2009;8:454-456. doi:10.1510/icvts.2008.197160
© 2009 European Association of Cardio-Thoracic Surgery

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Best evidence topic - Thoracic oncologic

Does video-assisted thoracoscopic decortication in advanced malignant mesothelioma improve prognosis?

Vivek Srivastavaa, Joel Dunningb,* and John Aua

a Department of Cardiothoracic Surgery, Victoria Hospital, Blackpool, UK
b Department of Cardiothoracic Surgery, James Cook University Hospital, Middlesbrough, UK

*Corresponding author. Tel./fax: +447801548122.

E-mail address: joeldunning{at}doctors.org.uk (J. Dunning).

A best evidence topic in thoracic surgery was written according to a structured protocol. The question addressed was: Does video-assisted thoracoscopic (VATS) decortication in advanced malignant mesothelioma improve prognosis? Altogether more than 25 papers were found using the reported search, of which five represented the best evidence to answer the clinical question. The authors, journal, date and country of publication, patient group studied, study type, relevant outcomes and results of these papers are tabulated. We conclude that VATS decortication is useful as a palliative measure in advanced malignant mesothelioma. VATS provides a diagnostic tool, yielding tissue for histological diagnosis. Secondly, drainage of effusion and pleurectomy/decortication improves the quality of life and may increase survival as well.

Key Words: Evidence based medicine; Mesothelioma; VATS; Survival; Prognosis







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