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Interact CardioVasc Thorac Surg 2008;7:656-657. doi:10.1510/icvts.2007.173104
© 2008 European Association of Cardio-Thoracic Surgery
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Ganesh Shanmugam
Roger Baskett
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Negative results - Cardiac general

Serotonin syndrome following cardiac surgery

Ganesh Shanmugama,*, Blaine Kentb, Turki Alsaiwadic and Roger Basketta

a Department of Cardiac Surgery, QEII Health Sciences Centre, Halifax Infirmary, 1796 Summer Street, Halifax, Nova Scotia B3L 4P7, Canada
b Department of Anaesthesiology, QEII Health Sciences Centre, Halifax Infirmary, 1796 Summer Street, Halifax, Nova Scotia B3L 4P7, Canada
c Department of Internal Medicine, QEII Health Sciences Centre, Halifax Infirmary, 1796 Summer Street, Halifax, Nova Scotia B3L 4P7, Canada

*Corresponding author. Tel.: +1 902 473 3808; fax: +1 902 473 4448.

E-mail address: sgunpat{at}hotmail.com (G. Shanmugam).

Selective serotonin reuptake inhibitors (SSRIs) are widely used to treat depression. We report a case of serotonin syndrome following cardiac surgery. This syndrome is rare in the cardiac literature. The clinical features, diagnosis and management of this unusual syndrome are described. In patients with polypharmacy, it is important to take cognisance of serotonergic antidepressants and anticipate their potential interactions with drugs used peri-operatively. Early recognition and treatment is important as this condition is potentially fatal.

Key Words: Serotonin syndrome; Mitral valve replacement; Paroxetine


Related Article

eComment: Serotonin syndrome: pharmacogenomics and treatment
Ioanna Koniari, Grigorios Tsigkas, and Efstratios Apostolakis
Interactive CardioVascular and Thoracic Surgery 2008 7: 657-658. [Full Text] [PDF]



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I. Koniari, G. Tsigkas, and E. Apostolakis
eComment: Serotonin syndrome: pharmacogenomics and treatment
Interactive CardioVascular and Thoracic Surgery, August 1, 2008; 7(4): 657 - 658.
[Full Text] [PDF]


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