Interact CardioVasc Thorac Surg 2008;7:389-395. doi:10.1510/icvts.2007.165795 © 2008 European Association of Cardio-Thoracic Surgery
Institutional report - Assisted circulation |
EuroSCORE directed intraaortic balloon pump placement in high-risk patients undergoing cardiac surgery – retrospective analysis of 267 patients
Claudius Dieza,
Rolf-Edgar Silbera,
Michael Wächnera,
Markus Stillera and
Hans-Stefan Hofmannb,*
a Martin-Luther-Universität Halle-Wittenberg, Department of Cardiothoracic Surgery, Ernst-Grube-Strasse 40, D-06097 Halle, Germany
b University Regensburg, Department of Thoracic Surgery, Franz-Josef-Strauss-Allee 11, D-93053 Regensburg, Germany
*Corresponding author. Tel.: +49 941 944 9846; fax: +49 941 9449802.
E-mail address: hans-stefan.hofmann{at}klinik.uni-regensburg.de (H.-S. Hofmann).
Objectives: Intraaortic ballon pump replacement (IABP) is the most widely used circulatory assist device today and is utilized in a wide range of serious cardiovascular conditions. We examined the effects on mortality of pre-, intra-, or postoperative IABP support in patients undergoing cardiac surgery compared to high-risk patients without IABP support. Methods: Between June 2001 and April 2004, 267 patients either received preoperative IABP support (n=62), an intra- or postoperative IABP (n=113) or had no IABP (n=92). Perioperative mortality was calculated with the EuroSCORE. Results: Patients with preoperative IABP and without IABP support had a lower ejection fraction [37 (29; 50) % and (39 (30; 53)) % vs. (50 (39; 65)) %, P=0.0001], more frequent unstable angina (38/62 and 53/92 vs. 37/113, P=0.0004) and recent myocardial infarctions (33/62 and 51/92 vs. 26/113, P=0.0001). The number of emergency procedures was also significantly higher (36/62 and 65/92 vs. 27/113, P 0.01). Patients with intra-, or postoperative IABP support and patients without IABP support had a longer ICU-stay [7.5 (5; 17.75)) and (7 (5; 15.5)) days vs. (6 (3; 10) days, P=0.023, P=0.015]. The overall hospital stay of patients without IABP [18.5 (14; 29) days] and intra-/postoperative IABP support [19, (14; 28) days] were significantly longer (P=0.007) compared to patients with preoperative support [14 (11.5; 20.5) days]. Whereas we found a trend towards reduced mortality in high-risk non-emergency patients with preoperative support, emergency patients and patients receiving intra- and postoperative support had significantly higher mortality rates than predicted by the EuroSCORE. Both emergency and non-emergency patients without IABP insertion had a significantly higher actual mortality than predicted (29.5% vs. 13.7%, P=0.03 and 38.1% vs. 26.3%, P<0.0001). The overall actual mortality between patients with preoperative IABP insertion and patients without preoperative IABP did not significantly differ (14/62 vs. 29/92, P=0.27). The EuroSCORE proved to be a valid predictor for perioperative mortality among high-risk non-emergency and emergency patients with preoperative IABP support at lower score sums, but failed at higher score sums (>8) and among patients with intra- and postoperative IABP insertion. Conclusion: Preoperative IABP support is indicated in high-risk non-emergency patients. The benefit of preoperative IABP insertion in emergency patients and intra- and postoperative IABP support still remains controversial and needs to be elucidated in further prospective, randomized studies.
Key Words: Intraaortic balloon pump; EuroSCORE; Mortality
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