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Pulmonary intestinal-type adenocarcinoma

^a Division of Thoracic Surgery, Matsue Red Cross Hospital, 200 Horomachi, Matsue, Shimane 690-8506, Japan
^b Division of Pathology, Matsue Red Cross Hospital, Shimane, Japan

*Corresponding author. Tel.: +81-852-24-2111; fax: +81-852-31-9783.

E-mail address: ryomaedamatsue{at}yahoo.co.jp (R. Maeda).

We report a rare case of pulmonary intestinal-type adenocarcinoma in a 69-year-old man. A computed tomographic scan of the chest and positron emission tomography revealed a well-defined nodule measuring 2.5 cmx2.5 cm in the right lower lobe with high ¹⁸F-fluorodeoxyglucose accumulation. Furthermore, sputum cytology tested positive for adenocarcinoma. Right lower lobectomy and systemic lymph node dissection were performed by video-assisted thoracic surgery (VATS). Histopathologically, the tumor was composed mainly of tall columnar cells with similarity to intestinal epithelia and colorectal carcinoma. Immunohistochemical staining was positive for cytokeratin 7 (CK7) and thyroid transcription factor-1 (TTF-1), whereas staining for cytokeratin 20 (CK20) was negative. The final diagnosis was primary pulmonary intestinal-type adenocarcinoma.

Key Words: Lung carcinoma; Intestinal-type adenocarcinoma

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