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Right ventricular failure after left ventricular assist device insertion: preoperative risk factors

^a Department of Anesthesiology and Critical Care – Policlinico San Matteo, via Donatello 7, 20020 Villa Cortese (MI), Pavia, Italy
^b Department of Cardiac Surgery – Policlinico San Matteo, Pavia, Italy

*Corresponding author. Tel.: +39-3470864903; fax: +39-0331449836.

E-mail address: salamina2003{at}libero.it (L. Santambrogio).

Right ventricular failure after left ventricular assist device placement is the major concern on weaning from cardiopulmonary bypass and it is one of the most serious complications in the postoperative period. This complication has a poor prognosis and is generally unpredictable. The identification of pre-operative risk factor for this serious complication is incomplete yet. In order to determine pre-operative risk for severe right ventricular failure after left ventricular assist device support we analyzed preoperative hemodynamics, laboratory data and characteristics of 48 patients who received Novacor (World Heart Corp., Ottawa, ON, Canada). We compared the data from the patients who developed right ventricular failure and the patients who did not. Right ventricular failure occurred in 16% of the patients. There was no significant difference between the groups in demographic characteristics. We identified as preoperative risk factors the pre-operative low mean pulmonary artery and the impairment of hepatic and renal function on laboratory data. Our results confirm in part the findings of the few previous studies. This information may be useful for the patient selection for isolated left ventricular assist device implantation, but other studies are necessary before establishing criteria for patient selection for univentricular support universally accepted.

Key Words: Cardiomyopathy; Heart-assist device; Heart failure

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				J. C. Matthews, T. M. Koelling, F. D. Pagani, and K. D. Aaronson The right ventricular failure risk score a pre-operative tool for assessing the risk of right ventricular failure in left ventricular assist device candidates. J. Am. Coll. Cardiol., June 3, 2008; 51(22): 2163 - 2172. [Abstract] [Full Text] [PDF]