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Is Sotalol more effective than standard beta-blockers for the prophylaxis of atrial fibrillation during cardiac surgery

Department of Cardiothoracic Surgery, Freeman Hospital, Freeman Road, High Heaton, Newcastle upon Tyne NE7 7AZ, UK

*Corresponding author. Tel.: +44(0)07801548122.

E-mail address: joeldunning{at}doctors.org.uk (J. Dunning).

A best evidence topic in cardiac surgery was written according to a structured protocol. The question addressed was whether prophylactic Sotalol was more effective than conventional ß blockers in the prevention of atrial fibrillation after cardiac surgery. Fifty-one papers were found of which eight presented the best evidence to answer the question. The author, journal, date and country of publication, patient group, relevant outcomes and weaknesses were tabulated. We conclude that prophylactic Sotalol may be more effective than ß blockers in the prevention of post operative atrial fibrillation, and should not cause an excess of side effects.

Key Words: Review; Evidence based medicine; Thoracic surgery; Atrial fibrillation; Sotalol

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