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Interact CardioVasc Thorac Surg 2005;4:75-76. doi:10.1510/icvts.2004.096784
© 2005 European Association of Cardio-Thoracic Surgery
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Case report - Thoracic gereral

Successful surgical treatment for life threatening metastatic thoracic and cervical pheochromocytoma

Tomoyasu Yashiro, MD1, Kazuhiro Yasufuku, MD1, Kenzo Hiroshima, MD2 and Takehiko Fujisawa, MD1

1 Department of Thoracic Surgery, Graduate school of medicine, Chiba University, 1-8-1 Inohana, Chuo-ku, Chiba 260-8670
2 Department of Basic Pathology, Graduate school of medicine, Chiba University, 1-8-1 Inohana, Chuo-ku, Chiba 260-8670

*Corresponding author: Takehiko Fujisawa, Professor and Chairman, Department of Thoracic Surgery, Graduate School of Medicine, Chiba University 1-8-1 Inohana, Chuo-ku, Chiba 260-8670 Japan. Tel.: +81-43-222-7171; fax: +81-43-226-2172. E-mail address: fujisawat{at}faculty.chiba-u.jp (T. Fujisawa).

A 53 year-old woman had been followed up since 1996 after receiving bilateral adrenalectomy for the treatment of bilateral adrenal pheochromocytoma in von Hippel-Lindau (VHL) disease. In March 2003, she suffered from cough, dizziness and faint, and was referred to our hospital. The radiographic findings exhibited the presence of hypervascular tumors in the left hilum, left apex of the lung and the left neck. Tumor progression was suspected to occlude the left main pulmonary artery and hormonal assays showed elevated levels of the plasma norepinephrine, which may cause fatal complications. Percutaneus needle biopsy of the left cervical tumor revealed metastatic pheochromocytoma. After embolization of the main feeding artery, surgical resection of the tumor resulted in control of excess catecholamine release and symptoms.

Key Words: Surgery; thoracic pheochromocytoma; embolization; von Hippel-Lindau disease

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