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Roland G. Demaria
Michel Carrier
Louis P. Perrault
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Interactive Cardiovascular and Thoracic Surgery 2:281-286(2003)
© 2003 European Association of Cardio-Thoracic Surgery

Work in progress report - Coronary

The Monoshunt: a new intracoronary shunt design to avoid distal endothelial dysfunction during off-pump coronary artery bypass (OPCAB)

Roland G. Demariaa,b, Olivier Maloa, Michel Carriera and Louis P. Perraulta,c,*

a Research Center and Department of Surgery, Montreal Heart Institute, 5000 Belanger Street East, Montreal, Quebec H1T 1C8, Canada
b Cardiovascular Surgery Unit, Arnaud de Villeneuve Teaching Hospital, Montpellier, France
c Department of Pharmacology, University of Montreal, Montreal, Quebec, Canada

* Corresponding author. Tel.: +1-514-376-3330 ext. 3471; fax: +1-514-376-1355
lpperrau{at}icm.umontreal.ca

Insertion of intracoronary shunts during off-pump coronary artery bypass surgery can induce a severe endothelial dysfunction. The purpose of this study was to propose a new intracoronary shunt design called Monoshunt, to avoid distal endothelial damage of the target artery in a porcine model. The use of the Monoshunt avoids distal endothelial denudation and allows distal coronary perfusion.

Key Words: Nitric oxide; Endothelium; Coronary disease




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