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Interactive Cardiovascular and Thoracic Surgery 2:46-52(2003)
© 2003 European Association of Cardio-Thoracic Surgery

Work in progress report - Cardiopulmonary bypass

The effects of hypothermic cardiopulmonary bypass on Doppler cerebral blood flow during the first 24 postoperative hours

Karim Bendjelida,*, Beate Pobleteb, Oskar Baenzigerc and Jacques-André Romanda

a Division of Surgical Intensive Care, Department APSIC, University Hospitals of Geneva, CH-1211 Geneva 14, Switzerland
b Division of Anaesthesiology, Hospital of Lucerne, Lucerne, Switzerland
c Department of Paediatrics, University Hospitals of Zurich, Zurich, Switzerland

* Corresponding author. Tel.: +41-22-382-7452; fax: +41-22-382-7455
karim.bendjelid{at}hcuge.ch

To provide understanding of influence of cardiopulmonary bypass (CPB) on cerebral blood flow (CBF), we investigated the effect of CPB on patients’ cerebral haemodynamic parameters. Twenty-three patients were prospectively enrolled. CBF was estimated by transcranial Doppler (TCD) to measure blood velocity in the middle cerebral artery (MVMCA), preoperatively (T0) and at four postoperative times (T1, T2, T3, T4). At times T2, T3 and T4, MVMCA remained at higher levels than T0 (). In the multivariate analysis PaCO2 was independently associated to MVMCA at times T1 and T2 (, , respectively) and temperature was independently associated with MVMCA at time T1 (). Thus, the present study showed an increase in CBF after CPB, that was correlated with raised temperature but not with decrease in haematocrit.

Key Words: Coronary artery bypass grafting; Human clinical study; Heart surgery; Rewarming




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G. Carbutti, J.-A. Romand, J.-S. Carballo, S.-M'h. Bendjelid, P. M. Suter, and K. Bendjelid
Transcranial Doppler: An Early Predictor of Ischemic Stroke After Cardiac Arrest?
Anesth. Analg., November 1, 2003; 97(5): 1262 - 1265.
[Abstract] [Full Text] [PDF]


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