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Malignant pleural mesothelioma: outcome of limited surgical management

^a Department of Thoracic Medicine, Harefield Hospital, Hill End Road, Harefield, Middlesex UB9 6JH, UK
^b Department of Cardiothoracic Surgery, Harefield Hospital, Hill End Road, Harefield, Middlesex UB9 6JH, UK

^* Corresponding author. Tel.: +44-1895-828558; fax: +44-1895-828528
cryotherapy{at}rbh.nthames.nhs.uk

This study presents data on limited surgical management of malignant pleural mesothelioma. We reviewed retrospectively 70 cases of the disease managed surgically over a 10 year period. Fifteen patients received only diagnostic direct pleural biopsy, 40 had video-assisted thoracoscopic, pleural biopsy and talc pleurodesis while 15 patients underwent thoracotomy and pleurectomy for disease confined to the pleura. There were two in-hospital deaths. Actuarial survival was significantly longer in the thoracotomy group (median 14 months vs. 6 months in the other two groups, ). Survival after limited surgical management of malignant mesothelioma is comparable to a previously reported more radical surgical approach.

Key Words: Pleural malignancy; Mesothelioma; Surgery