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Coronary artery dissection, combined aortic valve replacement and coronary bypass grafting in osteogenesis imperfecta

^a Division of Cardiology, Tampere University Hospital, 33521 Tampere, Finland
^b Division of Cardio-thoracic Surgery, Tampere University Hospital, 33521 Tampere, Finland

^* Corresponding author. Tel.: +358-3247-5111; fax: +358-3247-4157
markku.eskola{at}tays.fi

Osteogenesis imperfecta is an inherited connective tissue disorder. Aortic root dilation, aortic insufficiency and mitral valve prolapse are uncommon cardiovascular manifestations of osteogenesis imperfecta. Cardiac surgery in patients with osteogenesis imperfecta involves a high risk of complication rate. We report a case of coronary artery dissection induced by coronary angiogram in a patient with osteogenesis imperfecta and severe aortic regurgitation. In this case, the dissection of a coronary artery was not completely sealed by coronary stenting, and followed by successful combined aortic valve replacement and coronary artery bypass grafting on an emergency basis.

Key Words: Osteogenesis imperfecta; Dissection; Coronary vessels; Coronary artery bypass; Heart valve prosthesis implantation